New spectrophotometric method for simultaneous determination of metoprolol tartarate and hydrochlorthiazide in tablets

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New Spectrophotometric Method for Simultaneous determination of Metoprolol Tartarate and Hydrochlorthiazide in Tablets

The present work describes a two-wavelength method for simultaneous determination of metoprolol and hydrochlorthiazide in fixed dose combination tablet. The wavelengths selected for method were 257.8 nm, 282.9 nm and 315.0 nm. The absorbance difference at first two wavelengths was used for determination of metoprolol and the latter was used for determination of hydrochlorthiazide. The recovery ...

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2008

ISSN: 0250-474X

DOI: 10.4103/0250-474x.44606